Biblioteca sobre Multimorbilidad (1970–Actualidad)


Chris Salisbury, Mei-See Man, Katherine Chaplin, Cindy Mann, Peter Bower, Sara Brookes, Polly Duncan, Bridie Fitzpatrick, Caroline Gardner, Daisy M Gaunt, Bruce Guthrie, Sandra Hollinghurst, Bryar Kadir, Victoria Lee, John McLeod, Stewart W Mercer, Keith R Moffat, Emma Moody, Imran Rafi, Rebecca Robinson, Alison Shaw, Joanna Thorn (2019) A patient-centred intervention to improve the management of multimorbidity in general practice: the 3D RCT, Health Services and Delivery Research 7(5), p. 1-238, url, doi:10.3310/hsdr07050

Abdelmoneim Awad, Olivia Hanna (2019) Potentially inappropriate medication use among geriatric patients in primary care setting: A cross-sectional study using the Beers, STOPP, FORTA and MAI criteria., PloS one 14(6), p. e0218174, url, doi:10.1371/journal.pone.0218174

Louis Létinier, Sébastien Cossin, Yohann Mansiaux, Mickaël Arnaud, Francesco Salvo, Julien Bezin, Frantz Thiessard, Antoine Pariente (2019) Risk of Drug-Drug Interactions in Out-Hospital Drug Dispensings in France: Results From the DRUG-Drug Interaction Prevalence Study, Frontiers in Pharmacology 10(March), p. 1-9, doi:10.3389/fphar.2019.00265

Ziyad Alrabiah, Abdulaziz Alhossan, Sultan M. Alghadeer, Syed Wajid, Salmeen D. Babelghaith, Mohamed N. Al-Arifi (2019) Evaluation of community pharmacists’ knowledge about drug–drug interaction in Central Saudi Arabia, Saudi Pharmaceutical Journal 27(4), p. 463-466, King Saud University, url, doi:10.1016/j.jsps.2019.01.008

Mary Carpenter, Holly Berry, Allen L Pelletier (2019) Clinically Relevant Drug-Drug Interactions in Primary Care., American family physician 99(9), p. 558-564, American Family Physician, pubmed

C. Kympers, E. Tommelein, Ellen Van Leeuwen, K. Boussery, M. Petrovic, A. Somers (2019) Detection of potentially inappropriate prescribing in older patients with the GheOP³S-tool: completeness and clinical relevance, Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine 00(00), p. 1-11, Taylor & Francis, url, doi:10.1080/17843286.2019.1568353

Wubshet H. Tesfaye, Barbara C. Wimmer, Gregory M. Peterson, Ronald L. Castelino, Matthew D. Jose, Charlotte McKercher, Syed Tabish R. Zaidi (2019) The effect of hospitalization on potentially inappropriate medication use in older adults with chronic kidney disease, Current Medical Research and Opinion 0(0), p. -000, Taylor & Francis, url, doi:10.1080/03007995.2018.1560193

Wubshet H. Tesfaye, Gregory M. Peterson, Ronald L. Castelino, Charlotte McKercher, Matthew D. Jose, Barbara C. Wimmer, Syed Tabish R. Zaidi (2019) Medication Regimen Complexity and Hospital Readmission in Older Adults With Chronic Kidney Disease, Annals of Pharmacotherapy 53(1), p. 28-34, doi:10.1177/1060028018793419

Kristijonas Čyras, Tiago Oliveira (2019) Resolving Conflicts in Clinical Guidelines using Argumentation, url

By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel (2019) American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults., Journal of the American Geriatrics Society, url, doi:10.1111/jgs.15767

Priti P. Pednekar, Tamás Ágh, Maria Malmenäs, Amit D. Raval, Bryan M. Bennett, Bijan J. Borah, David S. Hutchins, Elizabeth Manias, Allison F. Williams, Mickaël Hiligsmann, Adina Turcu-Stiolica, John E. Zeber, Lusine Abrahamyan, Thomas J. Bunz, Andrew M. Peterson (2019) Methods for Measuring Multiple Medication Adherence: A Systematic Review–Report of the ISPOR Medication Adherence and Persistence Special Interest Group, Value in Health 22(2), p. 139-156, Elsevier, url, doi:10.1016/J.JVAL.2018.08.006


Christiane Muth, Lorenz Uhlmann, Walter E Haefeli, Justine Rochon, Marjan van den Akker, Rafael Perera, Corina Güthlin, Martin Beyer, Frank Oswald, Jose Maria Valderas, J André Knottnerus, Ferdinand M Gerlach, Sebastian Harder (2018) Effectiveness of a complex intervention on Prioritising Multimedication in Multimorbidity (PRIMUM) in primary care: results of a pragmatic cluster randomised controlled trial., BMJ open 8(2), p. e017740, pubmed, doi:10.1136/bmjopen-2017-017740

Faisal Shakeel, Muhammad Aamir, Ahmad Farooq Khan, Tayyiba Nader Khan, Samiullah Khan (2018) Epidemiology of potential drug-drug interactions in elderly population admitted to critical care units of Peshawar, Pakistan, BMC Pharmacology and Toxicology 19(1), p. 1-6, BMC Pharmacology and Toxicology, pubmed, doi:10.1186/s40360-018-0276-4

Virtudes Pérez-Jover, José J. Mira, Concepción Carratala-Munuera, Vicente F. Gil-Guillen, Josep Basora, Adriana López-Pineda, Domingo Orozco-Beltrán (2018) Inappropriate use of medication by elderly, polymedicated, or multipathological patients with chronic diseases, International Journal of Environmental Research and Public Health 15(2), doi:10.3390/ijerph15020310

Mette Heringa, Annet van der Heide, Annemieke Floor-Schreudering, Peter A G M De Smet, Marcel L Bouvy (2018) Better specification of triggers to reduce the number of drug interaction alerts in primary care., International journal of medical informatics 109, p. 96-102, doi:10.1016/j.ijmedinf.2017.11.005

Linda Ghali Koria, Tabish Syed Zaidi, Gregory Peterson, Prasad Nishtala, Paul J. Hannah, Ronald Castelino (2018) Impact of medication reviews on inappropriate prescribing in aged care, Current Medical Research and Opinion 34(5), p. 833-838, Taylor & Francis, url, doi:10.1080/03007995.2018.1424624

Andrew Whitman, Kathlene DeGregory, Amy Morris, Supriya Mohile, Erika Ramsdale (2018) Pharmacist-led medication assessment and deprescribing intervention for older adults with cancer and polypharmacy: a pilot study., Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 26(12), p. 4105-4113, pubmed, doi:10.1007/s00520-018-4281-3

Gibert Prudence, Cabaret Maud, Moulis Mélanie, Jean Luc Bosson, Boivin Jean-Emmanuel, Sebastien Chanoine, Allenet Benoit, Bedouch Pierrick, Gavazzi Gaëtan (2018) Optimizing medication use in elderly people in primary care: Impact of STOPP criteria on inappropriate prescriptions, Archives of Gerontology and Geriatrics 75(October 2017), p. 16-19, Elsevier, url, doi:10.1016/j.archger.2017.10.022

Cathal A. Cadogan, Cristín Ryan, Gerard J. Gormley, Jill J. Francis, Peter Passmore, Ngaire Kerse, Carmel M. Hughes (2018) A feasibility study of a theory-based intervention to improve appropriate polypharmacy for older people in primary care, Pilot and Feasibility Studies 4(1), p. 1-12, Pilot and Feasibility Studies, doi:10.1186/s40814-017-0166-3

Sangrak Lim, Kyubum Lee, Jaewoo Kang (2018) Drug drug interaction extraction from the literature using a recursive neural network., PloS one 13(1), p. e0190926, url, doi:10.1371/journal.pone.0190926

Marine L. Andersson, Ylva Böttiger, Henrik Kockum, Birgit Eiermann (2018) High Prevalence of Drug-Drug Interactions in Primary Health Care is Caused by Prescriptions from other Healthcare Units., Basic & clinical pharmacology & toxicology 122(5), p. 512-516, pubmed, doi:10.1111/bcpt.12939

Wu Yi Zheng, L. C. Richardson, L. Li, R. O. Day, J. I. Westbrook, M. T. Baysari (2018) Drug-drug interactions and their harmful effects in hospitalised patients: a systematic review and meta-analysis., European journal of clinical pharmacology 74(1), p. 15-27, pubmed, doi:10.1007/s00228-017-2357-5

María Sacramento Díaz-Carrasco, Miguel Almanchel-Rivadeneyra, Aina Tomás-Luiz, Sandra Pelegrín-Montesinos, Cristina Ramírez-Roig, Juan José Fernández-Ávila (2018) Observational study of drug-drug interactions in oncological inpatients., Farmacia Hospitalaria 42(1), p. 10-15, pubmed, doi:10.7399/fh.10857

Rawabi Aljadani, Mohammed Aseeri (2018) Prevalence of drug-drug interactions in geriatric patients at an ambulatory care pharmacy in a tertiary care teaching hospital., BMC research notes 11(234), p. 1-7, BioMed Central, url, doi:10.1186/s13104-018-3342-5

Yee Wei Shim, Siew Siang Chua, Hui Chin Wong, Syireen Alwi (2018) Collaborative intervention between pharmacists and physicians on elderly patients: a randomized controlled trial., Therapeutics and clinical risk management 14, p. 1115-1125, url, doi:10.2147/TCRM.S146218

Matthew McGuire, Ashley Barlow, Brooke Barlow, Kristine Swartz, Andrew Chapman, Laura T. Pizzi, Ginah Nightingale, Timothy Jacisin (2018) The prevalence of major drug-drug interactions in older adults with cancer and the role of clinical decision support software, Journal of Geriatric Oncology 9(5), p. 526-533, Elsevier Inc., url, doi:10.1016/j.jgo.2018.02.001

Varsha Shetty, Mukta N Chowta, Nithyananda Chowta K, Ashok Shenoy, Ashwin Kamath, Priyanka Kamath (2018) Evaluation of Potential Drug-Drug Interactions with Medications Prescribed to Geriatric Patients in a Tertiary Care Hospital., Journal of aging research 2018(Oct 9), p. 5728957, pubmed, doi:10.1155/2018/5728957

E. C.D. Castilho, A. M.M. Reis, T. L. Borges, L. D.C. Siqueira, A. I. Miasso (2018) Potential drug–drug interactions and polypharmacy in institutionalized elderly patients in a public hospital in Brazil, Journal of Psychiatric and Mental Health Nursing 25(1), p. 3-13, doi:10.1111/jpm.12431

Ylva Böttiger, Kari Laine, Tuomas Korhonen, Janne Lähdesmäki, Tero Shemeikka, Margaretha Julander, Maria Edlert, Marine L. Andersson (2018) Development and pilot testing of PHARAO—a decision support system for pharmacological risk assessment in the elderly, European Journal of Clinical Pharmacology 74(3), p. 365-371, European Journal of Clinical Pharmacology, doi:10.1007/s00228-017-2391-3

A Prados-Torres, B Poblador-Plou, A Gimeno-Miguel, A Calderón-Larrañaga, A Poncel-Falcó, L A Gimeno-Feliú, F González-Rubio, C Laguna-Berna, J Marta-Moreno, M Clerencia-Sierra, M Aza-Pascual-Salcedo, A C Bandrés-Liso, C Coscollar-Santaliestra, V Pico-Soler, J M Abad-Díez (2018) Cohort Profile: The Epidemiology of Chronic Diseases and Multimorbidity. The EpiChron Cohort Study, International Journal of Epidemiology(March), p. 1-9, url, doi:10.1093/ije/dyx259

The Academy of Medical Sciences (2018) Multimorbidity: a priority for global health research, p. 125, url

Albert Roso-Llorach, Concepción Violán, Quintí Foguet-Boreu, Teresa Rodriguez-Blanco, Mariona Pons-Vigués, Enriqueta Pujol-Ribera, Jose M Valderas (2018) Comparative analysis of methods for identifying multimorbidity patterns: A study of ‘real world’ data., BMJ open, doi:10.1136/bmjopen-2017-018986

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Andrew R Zullo, Shelly L Gray, Holly M Holmes, Zachary A Marcum (2018) Screening for Medication Appropriateness in Older Adults, Clinics in Geriatric Medicine 34(1), p. 39-54, url, doi:10.1016/j.cger.2017.09.003

Luís Monteiro, Tiago Maricoto, Isabel S Solha, Matilde Monteiro-Soares, Carlos Martins (2018) Computerised decision to reduce inappropriate medication in the elderly: a systematic review with meta-analysis protocol, BMJ Open 8(1), p. e018988, url, doi:10.1136/bmjopen-2017-018988


Susana Sánchez-Fidalgo, Maria Isabel Guzmán-Ramos, Mercedes Galván-Banqueri, Máximo Bernabeu-Wittel, Bernardo Santos-Ramos (2017) Prevalence of drug interactions in elderly patients with multimorbidity in primary care, International Journal of Clinical Pharmacy 39(2), p. 343-353, doi:10.1007/s11096-017-0439-1

González-Rojano et Al. (2017) No Title Utility of Checkthemeds® for Detection of Potentially Inappropriate Medication in Hospitalized Patients., Clinical Therapeutics 39(8), p. 37

Inés Cruz-Esteve, Josep Ramón Marsal-Mora, Gisela Galindo-Ortego, Leonardo Galván-Santiago, Marcos Serrano-Godoy, Esther Ribes-Murillo, Jordi Real-Gatius (2017) Análisis poblacional de la prescripción potencialmente inadecuada en ancianos según criterios STOPP/START (estudio STARTREC), Atencion Primaria 49(3), p. 166-176, Elsevier España, S.L.U., url, doi:10.1016/j.aprim.2016.02.013

Kuang Yuh; Dimayuga Paul C. and Shah Prediman K. Chyu (2017) Immunotherapy in non-metastatic non-small cell lung cancer:, Therapeutic Advances in Vaccines 5(2), p. 39-47, doi:10.1177/https

Morgan Price, Iryna Davies, Raymond Rusk, Mary Lesperance, Jens Weber (2017) Applying STOPP Guidelines in Primary Care Through Electronic Medical Record Decision Support: Randomized Control Trial Highlighting the Importance of Data Quality, JMIR Medical Informatics 5(2), p. e15, url, doi:10.2196/medinform.6226

Morgan Price, Iryna Davies, Raymond Rusk, Mary Lesperance, Jens Weber (2017) Applying STOPP Guidelines in Primary Care Through Electronic Medical Record Decision Support: Randomized Control Trial Highlighting the Importance of Data Quality, JMIR Medical Informatics 5(2), p. e15, url, doi:10.2196/medinform.6226

E. González-Rojano, S. Valdez Acosta, D. Romero Palacián, M. Hernández, F. Abad-Santos (2017) Utility of Checkthemeds® for Detection of Potentially Inappropriate Medication in Hospitalized Patients, Clinical Therapeutics 39(8), p. e37, url, doi:10.1016/j.clinthera.2017.05.116

() Application for an Electronic Medication Management Support System - Full Text View -, url


Nattawut Leelakanok, Andrea L. Holcombe, Brian C. Lund, Xiaomei Gu, Marin L. Schweizer (2017) Association between polypharmacy and death: A systematic review and meta-analysis, Journal of the American Pharmacists Association 57(6), p. 729-738.e10, American Pharmacists Association®, url, doi:10.1016/j.japh.2017.06.002

Alexandra Prados-Torres, Isabel del Cura-González, Daniel Prados-Torres, Juan A. López-Rodríguez, Francisca Leiva-Fernández, Amaia Calderón-Larrañaga, Fernando López-Verde, Luis A. Gimeno-Feliu, Esperanza Escortell-Mayor, Victoria Pico-Soler, Teresa Sanz-Cuesta, Mª Josefa Bujalance-Zafra, Mariel Morey-Montalvo, José Ramón Boxó-Cifuentes, Beatriz Poblador-Plou, José Manuel Fernández-Arquero, Francisca González-Rubio, María D. Ramiro-González, Carlos Coscollar-Santaliestra, Jesús Martín-Fernández, M. Pilar Mª Pilar Barnestein-Fonseca, José María Valderas-Martínez, Alessandra Marengoni, Christiane Muth, Mercedes Aza-Pascual-Salcedo, Antonio Poncel-Falcó, Ana Cristina Bandrés-Liso, Marta Alcaraz-Borrajo, José Ma Ruiz-San-Basilio, Ángel Mataix-San-Juan, Ana Ma López-León, Carmina Mateos-Sancho, Antonio Gimeno-Miguel, Virginia Hernández-Santiago, Francisca García-de Blas, Nuria García-Agua, Ricardo Rodríguez-Barrientos, Rubén Vázquez-Alarcón, Clara Laguna-Berna, Maria Isabel Márquez-Chamizo, Javier Marta-Moreno, Amaya Azcoaga-Lorenzo, José María Abad-Díez, Luis Sánchez-Perruca, Elena Polentinos-Castro, Mercedes Clerencia-Sierra, Gloria Ariza-Cardiel, Ana Isabel González-González, Milagros Rico-Blázquez, Marisa Rogero-Blanco, Ma Eugenia Tello-Bernabé, Mar Álvarez-Villalba, Mercedes Rumayor-Zarzuelo, Carmen Sánchez Celaya del Pozo, José Ignacio Torrente Garrido, Concepción García Aranda, Marina Pinilla Lafuente, Ma Teresa Delgado Marroquín, Ma José Gracia Molina, Javier Cuartero Bernal, Ma Victoria Asín Martín, Susana García Domínguez, Carlos Bolea Gorbea, Antonio Luis Oto Negre, Eugenio Galve Royo, Ma Begoña Abadía Taira, José Fernando Tomás Gutiérrez, José Porta Quintana, Valentina Martín Miguel, Esther Mateo de las Heras, Carmen Esteban Algora, Ma Teresa Martín Nasarre de Letosa, Elena Gascón del Prim, Noelia Sorinas Delgado, Ma Rosario Sanjuan Cortés, Teodoro Corrales Sánchez, Eustaquio Dendarieta Lucas, Ma del Pilar Mínguez Sorio, Adolfo Cajal Marzal, Eduardo Díaz Esperanza Mora García, Juan Carlos García Álvarez, Francisca García De Blas González, Cristina Guisado Pérez, Alberto López García Franco, Ma Elisa Viñuela Beneitez, Ana Ballarín González, Ma Isabel Ferrer Zapata, Esther Gómez Suarez, Fernanda Morales Ortiz, Lourdes Carolina Peláez Laguno, José Luis Quintana Gómez, Enrique Revilla Pascual, Francisco Ramón Abellán López, Carlos Casado Álvaro, Paulino Cubero González, Santiago Manuel Machín Hamalainen, Raquel Mateo Fernández, Ma Eloisa Rogero Blanco, Cesar Sánchez Arce, Elisa Ceresuela Wiesman, Jorge Olmedo Galindo, Claudia López Marcos, Soledad Lorenzo Borda, Juan Carlos Moreno José Leiva Fernández, Belén Muñoz Gómez, Enrique Rodríguez De Mingo, Juan Pedro Calvo Pascual, Margarita Gómez Barroso, Beatriz López Serrano, Ma Paloma Morso Peláez, Fernando Perales González, Julio Sánchez Salvador, Jeannet Dolores Sánchez Yépez, Ana Sosa Alonso, Ma del Mar Álvarez Villalba, Purificación Magán Tapia, Ma Angelica Fajardo Alcántara, Ma Canto De Hoyos Alonso, Rosario Iglesias González, Ma Aránzazu Murciano Antón, Manuel Antonio Alonso Pérez, Amaya Azcoaga Lorenzo, Ricardo De Felipe Medina, Amaya Nuria López Laguna, Eva Martínez Cid De Rivera, Iliana Serrano Flores, Ma Jesús Sousa José Alcaide Luisa Moya Rodríguez, Ma Soledad Núñez Isabel, Jesús Ma Redondo Sánchez, Pedro Sánchez Llanos, Lourdes Visedo Campillo, Javier Martín Izquierdo, Macarena Toro Sainz, Ma José Fernández Jiménez, Eduardo Díaz Esperanza Mora García, José Manuel Navarro Jiménez, Deborah Gil Gómez, Leovigildo Ginel Mendoza, Luz Pilar de la Mota Ybancos, Jaime Sasporte Genafo, Ma Jesús Sousa José Alcaide Luisa Moya Rodríguez, Elena Barceló Garach, Beatriz Caffarena de Arteaga, Ma Dolores Gallego Parrilla, Catalina Sánchez Morales, Ma del Mar Loubet Chasco, Irene Martínez Ríos, Elena Mateo Delgado, Esther Martín Aurioles, Sylvia Hazañas Ruiz, Nieves Muñoz Escalante, Enrique Leonés Salido, Ma Antonia Máximo Torres, Ma Jesús Sousa José Alcaide Luisa Moya Rodríguez, Encarnación Peláez Gálvez, José Manuel Ramírez Torres, Cristóbal Trillo Fernández, Ma Dolores García Martínez Cañavate, Ma del Mar Gil Mellado, Ma Victoria Muñoz Pradilla, Ma José Clavijo Peña, Juan Carlos Moreno José Leiva Fernández, Virginia Castillo Romero, Rafael Ángel Maqueda, Gloria Aycart Valdés, Miguel Domínguez Santaella, Ana Ma Fernández Vargas, Irene García García, Antonia González Rodríguez, Ma Carmen Molina Mendaño, Juana Morales Naranjo, Catalina Moreno Torres, Francisco Serrano Guerra, Josefa Bujalance-Zafra, Mariel Morey-Montalvo, José Ramón Boxó-Cifuentes, Beatriz Poblador-Plou, José Manuel Fernández-Arquero, Francisca González-Rubio, María D. Ramiro-González, Carlos Coscollar-Santaliestra (2017) Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy: Study protocol of a cluster randomized clinical trial (Multi-PAP project), Implementation Science 12(1), p. 1-10, Implementation Science, url, doi:10.1186/s13012-017-0584-x

Zafer Gören, Mahluga J Demirkapu, Gökçe Akpinar Acet, Sanda Çali, Medine Gülçebi Idriz Oğlu (2017) Potential drug-drug interactions among prescriptionsfor elderly patients in primary health care., Turkish journal of medical sciences 47(1), p. 47-54, pubmed, doi:10.3906/sag-1509-89

Susan E Merel, Douglas S Paauw (2017) Common Drug Side Effects and Drug-Drug Interactions in Elderly Adults in Primary Care., Journal of the American Geriatrics Society 65(7), p. 1578-1585, doi:10.1111/jgs.14870

Ruth Backman, Philip Weber, Alice M Turner, Mark Lee, Ian Litchfield (2017) Assessing the extent of drug interactions among patients with multimorbidity in primary and secondary care in the West Midlands (UK): a study protocol for the Mixed Methods Multimorbidity Study (MiMMS)., BMJ open 7(9), p. e016713, doi:10.1136/bmjopen-2017-016713

Dustin S. McEvoy, Dean F. Sittig, Thu-Trang Hickman, Skye Aaron, Angela Ai, Mary Amato, David W. Bauer, Gregory M. Fraser, Jeremy Harper, Angela Kennemer, Michael A. Krall, Christoph U. Lehmann, Sameer Malhotra, Daniel R. Murphy, Brandi O'Kelley, Lipika Samal, Richard Schreiber, Hardeep Singh, Eric J. Thomas, Carl V. Vartian, Jennifer Westmorland, Allison B. McCoy, Adam Wright (2017) Variation in high-priority drug-drug interaction alerts across institutions and electronic health records., Journal of the American Medical Informatics Association : JAMIA 24(2), p. 331-338, pubmed, doi:10.1093/jamia/ocw114

Ministerio de Sanidad Consumo y Bienestar Social (2017) Encuesta Nacional Salud España, Portal Estadístico, url

Syed Shahzad Hasan, Chia Siang Kow, Kaeshaelya Thiruchelvam, David Weng Kwai Chong, Syed Imran Ahmed (2017) An Evaluation of the Central Nervous System Medication Use and Frailty among Residents of Aged Care Homes in Malaysia, Neuroepidemiology 49(1-2), p. 82-90, doi:10.1159/000480433

Neža Muhič, Ales Mrhar, Miran Brvar (2017) Comparative analysis of three drug-drug interaction screening systems against probable clinically relevant drug-drug interactions: a prospective cohort study., European journal of clinical pharmacology 73(7), p. 875-882, pubmed, doi:10.1007/s00228-017-2232-4

Thalyta Renata Araújo Santos, Erika Aparecida Silveira, Lílian Varanda Pereira, Mércia Pandolfo Provin, Dione Marçal Lima, Rita Goreti Amaral (2017) Potential drug-drug interactions in older adults: A population-based study., Geriatrics & gerontology international 17(12), p. 2336-2346, pubmed, doi:10.1111/ggi.13070

Aitana Rodríguez-Pérez, Eva Rocío Alfaro-Lara, Sandra Albiñana-Perez, María Dolores Nieto-Martín, Jesús Díez-Manglano, Concepción Pérez-Guerrero, Bernardo Santos-Ramos (2017) Novel tool for deprescribing in chronic patients with multimorbidity: List of Evidence-Based Deprescribing for Chronic Patients criteria, Geriatrics and Gerontology International 17(11), p. 2200-2207, url, doi:10.1111/ggi.13062

Ozcan Basaran, Nesrin Filiz Basaran, Edip Guvenc Cekic, Ibrahim Altun, Volkan Dogan, Gurbet Ozge Mert, Kadir Ugur Mert, Fatih Akin, Mustafa Ozcan Soylu, Kadriye Memic Sancar, Murat Biteker (2017) PRescriptiOn PattERns of Oral Anticoagulants in Nonvalvular Atrial Fibrillation (PROPER study), Clinical and Applied Thrombosis/Hemostasis 23(4), p. 384-391, doi:10.1177/1076029615614395

Syed Shahzad Hasan, Chia Siang Kow, Rohit Kumar Verma, Syed Imran Ahmed, Piyush Mittal, David W.K. Chong (2017) An evaluation of medication appropriateness and frailty among residents of aged care homes in Malaysia, Medicine 96(35), p. e7929, url, doi:10.1097/MD.0000000000007929

Daniel Sevilla-Sánchez, Núria Molist-Brunet, Jordi Amblàs-Novellas, Joan Espaulella-Panicot, Carles Codina-Jané (2017) Potentially inappropriate medication at hospital admission in patients with palliative care needs, International Journal of Clinical Pharmacy 39(5), p. 1018-1030, doi:10.1007/s11096-017-0518-3

Alexander Thompson, Moray Nairn, Shaun Treweek, Bruce Guthrie, Angela Flynn, Siobhan Dumbreck, Phil Alderson, Katherine Payne (2017) Better guidelines for better care: accounting for multimorbidity in clinical guidelines – structured examination of exemplar guidelines and health economic modelling, Health Services and Delivery Research 5(16), p. 1-150, doi:10.3310/hsdr05160

K B Rakesh, Mukta N Chowta, Ashok K Shenoy, Rajeshwari Shastry, Sunil B Pai (2017) Evaluation of polypharmacy and appropriateness of prescription in geriatric patients: A cross-sectional study at a tertiary care hospital., Indian journal of pharmacology 49(1), p. 16-20, pubmed, doi:10.4103/0253-7613.201036

Alexandra Prados-Torres, Isabel del Cura-González, Juan Daniel Prados-Torres, Francisca Leiva-Fernández, Juan Antonio López-Rodríguez, Amaia Calderón-Larrañaga, Christiane Muth (2017) Multimorbilidad en medicina de familia y los principios Ariadne. Un enfoque centrado en la persona, Atención Primaria 49(5), p. 300-307, url, doi:10.1016/j.aprim.2016.11.013

Daniel Prados-Torres, Isabel Del Cura-González, Alexandra Prados-Torres (2017) [Towards a multimorbidity care model in Primary Care]., Atencion primaria 49(5), p. 261-262, pubmed, doi:10.1016/j.aprim.2016.11.004

Wálleri C. Reis, Aline F. Bonetti, Wallace E. Bottacin, Alcindo S. Reis, Thaís T. Souza, Roberto Pontarolo, Cassyano J. Correr, Fernando Fernandez-Llimos, Fernando Fernandez-Llimos (2017) Impact on process results of clinical decision support systems (CDSSs) applied to medication use: overview of systematic reviews., Pharmacy practice 15(4), p. 1036, Centro de Investigaciones y Publicaciones Farmaceuticas, pubmed, doi:10.18549/PharmPract.2017.04.1036

Nancy L. Schoenborn, Danelle Cayea, Matthew McNabney, Anushree Ray, Cynthia Boyd (2017) Prognosis communication with older patients with multimorbidity: Assessment after an educational intervention, Gerontology & Geriatrics Education 38(4), p. 471-481, Routledge, url, doi:10.1080/02701960.2015.1115983

Michaela L. Schiøtz, Anders Stockmarr, Dorte Høst, Charlotte Glümer, Anne Frølich (2017) Social disparities in the prevalence of multimorbidity – A register-based population study, BMC Public Health 17(1), p. 422, BioMed Central, url, doi:10.1186/s12889-017-4314-8

Xiaolin Xu, Gita D. Mishra, Mark Jones (2017) Evidence on multimorbidity from definition to intervention: An overview of systematic reviews, Ageing Research Reviews 37, p. 53-68, Elsevier, url, doi:10.1016/J.ARR.2017.05.003

Lars H Lund, Gianluigi Savarese (2017) Global Public Health Burden of Heart Failure, Citation: Cardiac Failure Review 23(11), p. 7-11, pdf, doi:10.15420/cfr.2016:25:2

Wálleri C Reis, Aline F Bonetti, Wallace E Bottacin, Alcindo S Reis, Thaís T Souza, Roberto Pontarolo, Cassyano J Correr, Fernando Fernandez-Llimos, Fernando Fernandez-Llimos (2017) Impact on process results of clinical decision support systems (CDSSs) applied to medication use: overview of systematic reviews., Pharmacy practice 15(4), p. 1036, Centro de Investigaciones y Publicaciones Farmaceuticas, pubmed, doi:10.18549/PharmPract.2017.04.1036

Cornelia Jäger, Tobias Freund, Jost Steinhäuser, Christian Stock, Johannes Krisam, Petra Kaufmann-Kolle, Michel Wensing, Joachim Szecsenyi (2017) Impact of a tailored program on the implementation of evidence-based recommendations for multimorbid patients with polypharmacy in primary care practices-results of a cluster-randomized controlled trial, Implementation Science 12(1), p. 1-13, Implementation Science, url, doi:10.1186/s13012-016-0535-y

Julien Castioni, Pedro Marques-Vidal, Nazanin Abolhassani, Peter Vollenweider, Gérard Waeber (2017) Prevalence and determinants of polypharmacy in Switzerland: Data from the CoLaus study, BMC Health Services Research 17(1), p. 1-9, BMC Health Services Research, doi:10.1186/s12913-017-2793-z

Michaela L. Schiøtz, Dorte Høst, Mikkel B. Christensen, Helena Domínguez, Yasmin Hamid, Merete Almind, Kim L. Sørensen, Thomas Saxild, Rikke Høgsbro Holm, Anne Frølich (2017) Quality of care for people with multimorbidity - A case series, BMC Health Services Research 17(1), p. 1-9, BMC Health Services Research, doi:10.1186/s12913-017-2724-z

Leyre Adrián-Arrieta, Juan Manuel Casas Fernández de Tejerina (2017) Patients' assessment of their chronic illness care, Atencion Primaria(xx), Elsevier España, S.L.U., url, doi:10.1016/j.aprim.2017.03.014


Terri R. Fried, Kristina Niehoff, Jennifer Tjia, Nancy Redeker, Mary K. Goldstein (2016) A Delphi process to address medication appropriateness for older persons with multiple chronic conditions, BMC Geriatrics 16(1), p. 1-8, BMC Geriatrics, url, doi:10.1186/s12877-016-0240-3

Pauline Anrys, Benoît Boland, Jean Marie Degryse, Jan De Lepeleire, Mirko Petrovic, Sophie Marien, Olivia Dalleur, Goedele Strauven, Veerle Foulon, Anne Spinewine (2016) STOPP/START version 2-development of software applications: Easier said than done?, Age and Ageing 45(5), p. 590-593, doi:10.1093/ageing/afw114

Kannayiram Alagiakrishnan, Patricia Wilson, Cheryl A Sadowski, Darryl Rolfson, Mark Ballermann, Allen Ausford, Karla Vermeer, Kunal Mohindra, Jacques Romney, Robert S Hayward (2016) Physicians' use of computerized clinical decision supports to improve medication management in the elderly - the Seniors Medication Alert and Review Technology intervention., Clinical interventions in aging 11, p. 73-81, doi:10.2147/CIA.S94126

Hugh Tilson, Lisa E. Hines, Gerald McEvoy, David M. Weinstein, Philip D. Hansten, Karl Matuszewski, Marianne le Comte, Stefanie Higby-Baker, Joseph T. Hanlon, Lynn Pezzullo, Kathleen Vieson, Amy L. Helwig, Shiew-Mei Huang, Anthony Perre, David W. Bates, John Poikonen, Michael A. Wittie, Amy J. Grizzle, Mary Brown, Daniel C. Malone (2016) Recommendations for selecting drug-drug interactions for clinical decision support., American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 73(8), p. 576-85, pubmed, doi:10.2146/ajhp150565

Akram Ahmad, MuhammadUmair Khan, Sadiqa Malik, GuruPrasad Mohanta, S Parimalakrishnan, Isha Patel, Sameer Dhingra (2016) Prescription patterns and appropriateness of antibiotics in the management of cough/cold and diarrhea in a rural tertiary care teaching hospital, Journal of Pharmacy And Bioallied Sciences 8(4), p. 335, url, doi:10.4103/0975-7406.199340

Jordan D. Haag, Amanda Z. Davis, Robert W. Hoel, Jeffrey J. Armon, Laura J. Odell, Ross A. Dierkhising, Paul Y. Takahashi (2016) Impact of pharmacist-provided medication therapy management on healthcare quality and utilization in recently discharged elderly patients, American Health and Drug Benefits 9(5), p. 259-267

Juliane Köberlein-Neu, Hugo Mennemann, Stefanie Hamacher, Isabel Waltering, Ulrich Jaehde, Corinna Schaffert, Olaf Rose (2016) Interprofessional medication management in patients with multiple morbidities - A cluster-randomized trial (the WestGem study), Deutsches Arzteblatt International 113(44), p. 731-740, doi:10.3238/arztebl.2016.0741

Mariko Teramura-Grönblad, Minna Raivio, Niina Savikko, Seija Muurinen, Helena Soini, Merja Suominen, Kaisu Pitkälä (2016) Potentially severe drug-drug interactions among older people and associations in assisted living facilities in Finland: a cross-sectional study., Scandinavian journal of primary health care 34(3), p. 250-7, url, doi:10.1080/02813432.2016.1207142

Heiner C. Bucher, Rita Achermann, Nadja Stohler, Christoph R. Meier (2016) Surveillance of Physicians Causing Potential Drug-Drug Interactions in Ambulatory Care: A Pilot Study in Switzerland., PloS one 11(1), p. e0147606, url, doi:10.1371/journal.pone.0147606

Pauline Anrys, Benoît Boland, Jean Marie Degryse, Jan De Lepeleire, Mirko Petrovic, Sophie Marien, Olivia Dalleur, Goedele Strauven, Veerle Foulon, Anne Spinewine (2016) STOPP/START version 2-development of software applications: Easier said than done?, Age and Ageing 45(5), p. 590-593, doi:10.1093/ageing/afw114

Anna Maria Grion, Umberto Gallo, Daniel Dumitru Tinjala, Julia Daragjati, Michele Loreggian, Giovanna Cardaci, Arduino Mangoni, Alberto Pilotto (2016) A New Computer-Based Tool to Reduce Potentially Inappropriate Prescriptions in Hospitalized Geriatric Patients, Drugs and Aging 33(4), p. 267-275, Springer International Publishing, doi:10.1007/s40266-015-0340-3

A. Fajreldines, J. Insua, E. Schnitzler (2016) Prevalencia de prescripción potencialmente inapropiada de medicamentos en adultos mayores, Revista de Calidad Asistencial 31(5), p. 279-284, SECA, url, doi:10.1016/j.cali.2015.12.009

David O Riordan, Kieran A Walsh, Rose Galvin, Carol Sinnott, Patricia M Kearney, Stephen Byrne (2016) The effect of pharmacist-led interventions in optimising prescribing in older adults in primary care: A systematic review., SAGE open medicine 4(August), p. 2050312116652568, pubmed, doi:10.1177/2050312116652568

Thongchai Jaa Nichkhun, Akara F Sombat, Winai Ampol Chatree, Sorapong K Mitr (2016) Prevalence of PIMs using Beers criteria and STOPP in the geriatric outpatient care 4(6), p. 372-377

T. M. Toivo, J. A.V. Mikkola, K. Laine, M. Airaksinen (2016) Identifying high risk medications causing potential drug-drug interactions in outpatients: A prescription database study based on an online surveillance system, Research in Social and Administrative Pharmacy 12(4), p. 559-568, pubmed, doi:10.1016/j.sapharm.2015.09.004

Cliona Lewis, Emma Wallace, Lorraine Kyle, Walter Cullen, Susan M. Smith, Lorraine Kyne, Walter Cullen, Susan M. Smith (2016) Training doctors to manage patients with multimorbidity: a systematic review, Journal of Comorbidity 2016(2), p. 85-94, url, doi:10.15256/joc.2016.6.87

Tiago Taveira-Gomes, Patrícia Ferreira, Isabel Taveira-Gomes, Milton Severo, Maria Amélia Ferreira (2016) What Are We Looking for in Computer-Based Learning Interventions in Medical Education? A Systematic Review., Journal of medical Internet research 18(8), p. e204, JMIR Publications Inc., pubmed, doi:10.2196/jmir.5461

Denis O'Mahony, Paul F. Gallagher, Amanda H. Lavan, Paul F. Gallagher, Denis O’Mahony, Denis O'Mahony, Paul F. Gallagher, Amanda H. Lavan (2016) Methods to reduce prescribing errors in elderly patients with multimorbidity, Clinical Interventions in Aging 11, p. 857-866, Dove Press, url, doi:10.2147/CIA.S80280

Susan M Smith, Emma Wallace, Tom O'Dowd, Martin Fortin (2016) Interventions for improving outcomes in patients with multimorbidity in primary care and community settings., The Cochrane database of systematic reviews 3(4), p. CD006560, pubmed, doi:10.1002/14651858.CD006560.pub3

David Monterde, Emili Vela, Montse Clèries (2016) Los grupos de morbilidad ajustados: nuevo agrupador de morbilidad poblacional de utilidad en el ámbito de la atención primaria, Atención Primaria 48(10), p. 674-682, doi:10.1016/j.aprim.2016.06.003

Petra Hopman, François G. Schellevis, Mieke Rijken (2016) Health-related needs of people with multiple chronic diseases: differences and underlying factors, Quality of Life Research 25(3), p. 651-660, pubmed, doi:10.1007/s11136-015-1102-8

Andrea Gruneir, Susan E. Bronskill, Colleen J. Maxwell, Yu Qing Bai, Anna J. Kone, Kednapa Thavorn, Yelena Petrosyan, Andrew Calzavara, Walter P. Wodchis (2016) The association between multimorbidity and hospitalization is modified by individual demographics and physician continuity of care: a retrospective cohort study, BMC Health Services Research 16(1), p. 154, BioMed Central, url, doi:10.1186/s12913-016-1415-5

Jean Yves Le Reste, Patrice Nabbe, Djurdjica Lazic, Radost Assenova, Heidrun Lingner, Slawomir Czachowski, Stella Argyriadou, Agnieszka Sowinska, Charilaos Lygidakis, Christa Doerr, Ana Claveria, Bernard Le Floch, Jeremy Derriennic, Harm Van Marwijk, Paul Van Royen (2016) How do general practitioners recognize the definition of multimorbidity? A European qualitative study, European Journal of General Practice 22(3), p. 159-168, Taylor & Francis, url, doi:10.3109/13814788.2015.1136619

Jacqui Wise (2016) Patients with multimorbidity need longer GP consultations, says RCGP., BMJ (Clinical research ed.) 355, p. i5961, British Medical Journal Publishing Group, pubmed, doi:10.1136/BMJ.I5961

Filipe Prazeres, Luiz Santiago (2016) The Knowledge, Awareness, and Practices of Portuguese General Practitioners Regarding Multimorbidity and its Management: Qualitative Perspectives from Open-Ended Questions, International Journal of Environmental Research and Public Health 13(11), p. 1097, Multidisciplinary Digital Publishing Institute, url, doi:10.3390/ijerph13111097

MD. Cano Pérez, MV. Castell-Alcalá, R. Queipo-Matas, Martín-Martín S., C. Mateo-Pascual, Otero-Puime A. (2016) Utilización de servicios de atención primaria, atención especializada y consumo de medicamentos por la población de 65 años y más en la Comunidad de Madrid, Rev Esp Salud Publica 90(3), p. 1-11, url

National Institute for Health and Care Excellence (NICE) (2016) Multimorbidity: clinical assessment and management. Guidance and guidelines, NICE, url

Jeffrey C. Munson, Julie P. W. Bynum, John-Erik Bell, Robert Cantu, Christine McDonough, Qianfei Wang, Tor D. Tosteson, Anna N. A. Tosteson (2016) Patterns of Prescription Drug Use Before and After Fragility Fracture, JAMA Internal Medicine 176(10), p. 1531, url, doi:10.1001/jamainternmed.2016.4814

SM Smith, E Wallace, O T Dowd, M Fortin (2016) Intervenions for improving outcomes in patients with multimorbidit y in primary care and community settings ( Review ), The Cochrane Collaboration(3), doi:10.1002/

Miller P Alldred DP, Kennedy MC, Hughes C, Timothy F Chen (2016) Interventions to optimise prescribing for older people in care homes ( Review ) SUMMARY OF FINDINGS FOR THE MAIN COMPARISON, Cochrane Database of Systematic Reviews(2), p. 68, doi:10.1002/

Andreas Sönnichsen, Ulrike S. Trampisch, Anja Rieckert, Giuliano Piccoliori, Anna Vögele, Maria Flamm, Tim Johansson, Aneez Esmail, David Reeves, Christin Löffler, Jennifer Höck, Renate Klaassen-Mielke, Hans Joachim Trampisch, Ilkka Kunnamo (2016) Polypharmacy in chronic diseases-Reduction of Inappropriate Medication and Adverse drug events in older populations by electronic Decision Support (PRIMA-eDS): Study protocol for a randomized controlled trial, Trials 17(1), p. 1-9, Trials, doi:10.1186/s13063-016-1177-8

Luis A Gimeno-feliu, Amaia Calderón-larrañaga, Esperanza Diaz, Beatriz Poblador-plou, Rosa Macipe-costa, Alexandra Prados-torres (2016) Global healthcare use by immigrants in Spain according to morbidity burden , area of origin , and length of stay, BMC Public Health, BMC Public Health, url, doi:10.1186/s12889-016-3127-5

World Health Organization (2016) Multimorbidity: Technical Series on Safer Primary Care

National Institute for Health and Care Excellence (2016) Multimorbidity: clinical assessment and management(May), url

Christiane Muth, Sebastian Harder, Lorenz Uhlmann, Justine Rochon, Birgit Fullerton, Corina Güthlin, Antje Erler, Martin Beyer, Marjan van den Akker, Rafael Perera, André Knottnerus, Jose M Valderas, Ferdinand M Gerlach, Walter E Haefeli (2016) Pilot study to test the feasibility of a trial design and complex intervention on PRI oritising MU ltimedication in M ultimorbidity in general practices (PRIMUM pilot), BMJ Open 6(7), p. e011613, url, doi:10.1136/bmjopen-2016-011613

Andrew D Wilson, Susan Childs, Daniela C Gonçalves-Bradley, Greg J Irving (2016) Interventions to increase or decrease the length of primary care physicians' consultation., The Cochrane database of systematic reviews 8(8), p. CD003540, pubmed, doi:10.1002/14651858.CD003540.pub3

Mohammed A A Mohammed, Rebekah J J Moles, Timothy F F Chen (2016) Medication-related burden and patients' lived experience with medicine: a systematic review and metasynthesis of qualitative studies., BMJ open 6(2), p. e010035, url, doi:10.1136/bmjopen-2015-010035

Francisca Muñoz Cobos (2016) Cambio de modelo de atención sanitaria, Med fam Andal 17(1), p. 49-64

Sandra H H van Oostrom, Ronald Gijsen, Irina Stirbu, Joke C JC Joke C Korevaar, FG Francois G G Schellevis, HS H. Susan J Susan J HSJ Picavet, Nancy Hoeymans, BW Ward, JS Schiller, VM Freid, AB Bernstein, MA Bush, E Erdem, A Erler, T Bodenheimer, R Baker, N Goodwin, C Spreeuwenberg, HJ Vrijhoef, PL Remington, RC Brownson, Nancy Hoeymans, Ronald Gijsen, LC Slobbe, J O'Halloran, GC Miller, H Britt, MC Biermans, RA Verheij, DH de de Bakker, GA Zielhuis, PF de Vries de Vries Robbe, M de de Klerk, FY Wong, J Roels, J van den van den Brakel, M Fortin, M Stewart, ME Poitras, J Almirall, H Maddocks, MT Schram, D Frijters, EH van de van de Lisdonk, J Ploemacher, AJ de de Craen, MW de de Waal, B Meinow, MG Parker, I Kareholt, M Thorslund, AA Uijen, EH van de van de Lisdonk, KD Bertakis, R Azari, LJ Helms, EJ Callahan, JA Robbins, G Hulsegge, HS H. Susan J Susan J HSJ Picavet, A Blokstra, AC Nooyens, AM Spijkerman, YT van der van der Schouw, M Karanikolos, P Mladovsky, J Cylus, S Thomson, S Basu, D Stuckler, SL Merkus, KA Holte, MA Huysmans, W van van Mechelen, AJ van der van der Beek, H Swinkels, H Galenkamp, M Huisman, AW Braam, FG Francois G G Schellevis, DJ Deeg, LG Glynn, JM Valderas, P Healy, E Burke, J Newell, P Gillespie, H van den van den Bussche, G Schon, T Kolonko, H Hansen, K Wegscheider, G Glaeske, SH van van Oostrom, HS H. Susan J Susan J HSJ Picavet, SR de de Bruin, Irina Stirbu, Joke C JC Joke C Korevaar, FG Francois G G Schellevis (2016) Time Trends in Prevalence of Chronic Diseases and Multimorbidity Not Only due to Aging: Data from General Practices and Health Surveys, Plos One 11(8), p. e0160264, url, doi:10.1371/journal.pone.0160264

Eva Rocío Alfaro-Lara, Bernardo Santos-Ramos, Ana Isabel González-Méndez, Mercedes Galván-Banqueri, María Dolores Vega-Coca, María Dolores Nieto-Martín, Manuel Ollero-Baturone, Concepción Pérez-Guerrero (2016) [Medication reconciliation on hospital admission in patients with multiple chronic diseases using a standardised methodology]., Revista española de geriatría y gerontología 48(3), p. 103-8, pubmed, doi:10.1016/j.regg.2012.11.011

() National Clinical Guideline Centre Multimorbidity: clinical assessment and management Multimorbidity: assessment, prioritisation and management of care for people with commonly occurring multimorbidity Multimorbidity: clinical assessment and management


Wilson Ad, S Childs, Gonçalves-bradley Dc, Irving Gj (2016) Interventions to increase or decrease the length of primary care physicians ’ consultation ( Review ) SUMMARY OF FINDINGS FOR THE MAIN COMPARISON(8), doi:10.1002/

Petra Hopman, Simone R de Bruin, Maria João Forjaz, Carmen Rodriguez-Blazquez, Giuseppe Tonnara, Lidwien C Lemmens, Graziano Onder, Caroline A Baan, Mieke Rijken (2016) Effectiveness of comprehensive care programs for patients with multiple chronic conditions or frailty: a systematic literature review, Health Policy 120(7), p. 818-832, Elsevier Ireland Ltd, url, doi:10.1016/j.healthpol.2016.04.002

Mei-See Man, Katherine Chaplin, Cindy Mann, Peter Bower, Sara Brookes, Bridie Fitzpatrick, Bruce Guthrie, Alison Shaw, Sandra Hollinghurst, Stewart Mercer, Imran Rafi, Joanna Thorn, Chris Salisbury (2016) Improving the management of multimorbidity in general practice: protocol of a cluster randomised controlled trial (The 3D Study)., BMJ open 6(4), p. e011261, pubmed, doi:10.1136/bmjopen-2016-011261

Carmel M. Martin (2016) Multimorbidity: Through a Glass Darkly, The Value of Systems and Complexity Sciences for Healthcare, p. 121-131, Cham: Springer International Publishing, url, doi:10.1007/978-3-319-26221-5_10

Janet Heaton, Nicky Britten, Janet Krska, Joanne Reeve (2016) Person-centred medicines optimisation policy in England: an agenda for research on polypharmacy., Primary health care research & development, p. 1-11, pubmed, doi:10.1017/S1463423616000207

Stuart J. Pocock, Gregg W. Stone (2016) The Primary Outcome Fails - What Next?, The New England journal of medicine 375(9), Jeffrey M. Drazen, David P. Harrington, John J.V. McMurray, James H. Ware, Janet Woodcock (ed.), p. 861-70, url, doi:10.1056/NEJMra1510064

Stewart W. Mercer, Bridie Fitzpatrick, Bruce Guthrie, Elisabeth Fenwick, Eleanor Grieve, Kenny Lawson, Nicki Boyer, Alex McConnachie, Suzanne M. Lloyd, Rosaleen O’Brien, Graham C. M. Watt, Sally Wyke (2016) The CARE Plus study – a whole-system intervention to improve quality of life of primary care patients with multimorbidity in areas of high socioeconomic deprivation: exploratory cluster randomised controlled trial and cost-utility analysis, BMC Medicine 14(1), p. 88, BMC Medicine, url, doi:10.1186/s12916-016-0634-2

(2016) Polimedicado, url

A Marengoni, R J F Melis, A Prados Torres, G Onder (2016) Multimorbidity : Epidemiology and Models of Care 2016(1), p. 4-6


Alessandra Marengoni, Graziano Onder (2015) Guidelines, polypharmacy, and drug-drug interactions in patients with multimorbidity: A cascade of failure, BMJ (Online) 350(March), p. 10-11, url, doi:10.1136/bmj.h1059

By the American Geriatrics Society 2015 Beers Criteria Update Expert Panel (2015) American Geriatrics Society 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults., Journal of the American Geriatrics Society 63(11), p. 2227-46, pubmed, doi:10.1111/jgs.13702

Anna J. Koné Pefoyo, Susan E. Bronskill, Andrea Gruneir, Andrew Calzavara, Kednapa Thavorn, Yelena Petrosyan, Colleen J. Maxwell, Yuqing Bai, Walter P. Wodchis (2015) The increasing burden and complexity of multimorbidity, BMC Public Health 15(1), p. 415, ???, url, doi:10.1186/s12889-015-1733-2

Organización Mundial de la Salud (OMS) (2015) Informe mundial sobre el envejecimiento y la salud, Journal of Chemical Information and Modeling 53(9), p. 1689-1699, doi:10.1017/CBO9781107415324.004

Akram Ahmad, Muhammad Umair Khan, Irfanul Haque, Rahul Ivan, Ram Dasari, Megha Revanker, A. Pravina, Sheetal Kuriakose (2015) Evaluation of potential drug - drug interactions in general medicine ward of teaching hospital in Southern India, Journal of Clinical and Diagnostic Research 9(2), p. FC10-FC13, pubmed, doi:10.7860/JCDR/2015/11264.5608

Asma Ben Abacha, Md Faisal Mahbub Chowdhury, Aikaterini Karanasiou, Yassine Mrabet, Alberto Lavelli, Pierre Zweigenbaum (2015) Text mining for pharmacovigilance: Using machine learning for drug name recognition and drug-drug interaction extraction and classification, Journal of Biomedical Informatics 58, p. 122-132, Elsevier Inc., url, doi:10.1016/j.jbi.2015.09.015

Denis O'mahony, David O'sullivan, Stephen Byrne, Marie Noelle O'connor, Cristin Ryan, Paul Gallagher (2015) STOPP/START criteria for potentially inappropriate prescribing in older people: Version 2, Age and Ageing 44(2), p. 213-218, doi:10.1093/ageing/afu145

() Medición de la Salud y la Discapacidad Manual para el Cuestionario de Evaluación de la Discapacidad de la OMS, url


Serkan Ayvaz, John Horn, Oktie Hassanzadeh, Qian Zhu, Johann Stan, Nicholas P. Tatonetti, Santiago Vilar, Mathias Brochhausen, Matthias Samwald, Majid Rastegar-Mojarad, Michel Dumontier, Richard D. Boyce (2015) Toward a complete dataset of drug-drug interaction information from publicly available sources., Journal of biomedical informatics 55, p. 206-17, Elsevier Inc., url, doi:10.1016/j.jbi.2015.04.006

Sun Kim, Haibin Liu, Lana Yeganova, W. John Wilbur (2015) Extracting drug-drug interactions from literature using a rich feature-based linear kernel approach., Journal of biomedical informatics 55, p. 23-30, Elsevier Inc., url, doi:10.1016/j.jbi.2015.03.002

Emanuel Raschi, Carlo Piccinni, Vincenzo Signoretta, Lucio Lionello, Silvia Bonezzi, Marcello Delfino, Lucia Di Candia, Lucio Di Castri, Fabio Pieraccini, Daniela Carati, Elisabetta Poluzzi, Fabrizio De Ponti, Emilia-Romagna elderly poly-treated patients research group (2015) Clinically important drug-drug interactions in poly-treated elderly outpatients: a campaign to improve appropriateness in general practice., British journal of clinical pharmacology 80(6), p. 1411-20, pubmed, doi:10.1111/bcp.12754

Damià Barris Blundell (2015) Revisión de medicación según criterios STOPP/START en pacientes mayores del servicio de sistema personalizado de dosificación de medicamentos de una farmacia comunitaria, Farmacéuticos Comunitarios 7(2), p. 31-36, doi:10.5672/FC.2173-9218.(2015/Vol7).002.05

Carolin Wolf, Anne Pauly, Andreas Mayr, Teja Grömer, Bernd Lenz, Johannes Kornhuber, Kristina Friedland (2015) Pharmacist-led medication reviews to identify and collaboratively resolve drug-related problems in psychiatry-a controlled, clinical trial, PLoS ONE 10(11), p. 1-18, doi:10.1371/journal.pone.0142011

Pedro Gabriel Duarte Domingues, Rui Carneiro, Isabel Costa, Carolina Monteiro, Yulyia Shvetz, Ana C. Barbosa, Pedro Azevedo (2015) Therapeutic futility in cancer patients at the time of palliative care transition: An analysis with a modified version of the Medication Appropriateness Index, Palliative Medicine 29(7), p. 643-651, doi:10.1177/0269216315573687

Klaas Van Der Spek, Debby L. Gerritsen, Martin Smalbrugge, Marjorie H.J.M.G. Nelissen-Vrancken, Roland B. Wetzels, Claudia H.W. Smeets, Sytse U. Zuidema, Raymond T.C.M. Koopmans (2015) A reliable and valid index was developed to measure appropriate psychotropic drug use in dementia, Journal of Clinical Epidemiology 68(8), p. 903-912, Elsevier Inc, url, doi:10.1016/j.jclinepi.2015.03.012

A. Alassaad, H. Melhus, M. Hammarlund-Udenaes, M. Bertilsson, U. Gillespie, J. Sundstrom (2015) A tool for prediction of risk of rehospitalisation and mortality in the hospitalised elderly: secondary analysis of clinical trial data, BMJ Open 5(2), p. e007259-e007259, url, doi:10.1136/bmjopen-2014-007259

Bruce Guthrie, Boikanyo Makubate, Virginia Hernandez-Santiago, Tobias Dreischulte (2015) The rising tide of polypharmacy and drug-drug interactions: Population database analysis 1995-2010, BMC Medicine 13(1), p. 1-10, ???, url, doi:10.1186/s12916-015-0322-7

Siobhan Dumbreck, Angela Flynn, Moray Nairn, Martin Wilson, Shaun Treweek, Stewart W. Mercer, Phil Alderson, Alex Thompson, Katherine Payne, Bruce Guthrie (2015) Drug-disease and drug-drug interactions: systematic examination of recommendations in 12 UK national clinical guidelines., BMJ (Clinical research ed.) 350, p. h949, pubmed, doi:10.1136/bmj.h949

Sarah Maguire, Karena Hanley, Kevin Quinn, John Sheeran, Paul Stewart (2015) Teaching multimorbidity management to GP trainees: a pilot workshop, Education for Primary Care 26(6), p. 410-415, Taylor & Francis, url, doi:10.1080/14739879.2015.1101848

Paolo Fraccaro, Mercedes Arguello Castelerio, John Ainsworth, Iain Buchan (2015) Adoption of Clinical Decision Support in Multimorbidity: A Systematic Review, JMIR Medical Informatics 3(1), p. e4, url, doi:10.2196/medinform.3503

Sarah Yardley, Elizabeth Cottrell, Eliot Rees, Joanne Protheroe (2015) Modelling successful primary care for multimorbidity: a realist synthesis of successes and failures in concurrent learning and healthcare delivery, BMC Fam Pract 16(1), p. 23, BioMed Central, url, doi:10.1186/s12875-015-0234-9

Jose M. Valderas (2015) Multimorbidity, not a health condition or complexity by another name, European Journal of General Practice 21(4), p. 213-214, url, doi:10.3109/13814788.2015.1108404

Jean Yves Yves Le Reste, Patrice Nabbe, Charles Rivet, Charilaos Lygidakis, Christa Doerr, Slawomir Czachowski, Heidrun Lingner, Stella Argyriadou, Djurdjica Lazic, Radost Assenova, Melida Hasaganic, Miquel Angel Angel Munoz, Hans Thulesius, Bernard Le Floch, Jeremy Derriennic, Agnieska Sowinska, Harm Van Marwijk, Claire Lietard, Paul Van Royen (2015) The European general practice research network presents the translations of its comprehensive definition of multimorbidity in family medicine in ten European languages., PloS one 10(1), Leonardo M. Fabbri (ed.), p. e0115796, Public Library of Science, pubmed, doi:10.1371/journal.pone.0115796

Susann Hasler, Oliver Senn, Thomas Rosemann, Stefan Neuner-Jehle (2015) Effect of a patient-centered drug review on polypharmacy in primary care patients: Study protocol for a cluster-randomized controlled trial, Trials 16(1), p. 380, pubmed, doi:10.1186/s13063-015-0915-7

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